P40Plus / Supplement Facts:

http://www.westmartinlongevity.com/products/p40plus/#divinfo3

Beta-Sitosterol and Enlarged Prostate (Partial Review)

In a study published in Lancet, 200 men with BPH took 20 mg of beta-sitosterol or placebo three times a day for six months. At the end of six months, the researchers observed an increase in maximum urine flow rate from a baseline of 9.9 mL/second to 15.2 mL/second, as well as a decrease in mean residual urinary volume from 65.8 mL at baseline to 30.4 mL. No changes were reported in men who had taken placebo.

(Berges 1995)

After unblinding the 6 month trial from the previous Berges study (1995), men in both the beta-sitosterol and placebo groups were given the option of staying on the trial for an additional 12 months while taking beta-sitosterol. A total of 117 men took 20 mg of beta-sitosterol three times a day. In a follow-up study, the authors found that beta-sitosterol health benefits included the ability to maintain the advantages achieved previously for an additional 18 months of observation. (Berges 2000)

In 1997, a six-month double-blind, placebo-controlled clinical trial evaluated the efficacy and safety of 130 mg free beta-sitosterol compared with placebo in 177 men who had BPH. The International Prostate Symptom Score (IPSS) was the main outcome variable. Also evaluated were changes in quality of life, peak urinary flow rate (Qmax), and post-void residual urinary volume. After six months, the researchers saw significant improvements in all factors over placebo in men who received beta-sitosterol. The authors concluded that “these results show that beta-sitosterol is an effective option in the treatment of BPH.” (Klippel 1997)

A subsequent review of all existing studies at that time (2000) of beta-sitosterol in men who had BPH was reported in Cochrane Databases of Systematic Reviews. Four randomized, placebo-controlled, double-blind trials that involved 519 men were evaluated. The investigators found that beta-sitosterols improved urinary symptom scores, peak urine flow, and residual volume. The reviewers concluded that beta-sitosterols “improve urinary symptoms and flow measures.” (Wilt 1999)

Sign up for our Video Newsletter & Informative Reports